On the road, in a new Southeastern Conference environment, Vanderbilt quickly jumped ahead of the 22nd ranked team in the country.
Then the Commodores ran into a buzzsaw.
Missouri ripped off an unimaginable 38-4 run in the first half and never looked back as Vanderbilt suffered an 81-59 loss on Saturday. The defeat snapped the Commodores' two-game win streak.
The Tigers (15-4, 4-2) jumped out to a 49-20 halftime lead. Vanderbilt (8-10, 2-4) opened the second half with a 19-7 run but couldn’t get closer than 17 points.
The Commodores led 11-8 early in the second half before Missouri took off and scored nearly 40 points in almost 13 minutes. The Tigers made seven 3-pointers during the stretch and were up 46-15 with 2:40 before halftime.
Vanderbilt entered with the league’s best 3-point defense, allowing SEC opponents to make just 25.5 percent. Missouri, though, made 11 of 21.
The Commodores also struggled to keep the Tigers off the boards. Missouri dominated the glass 40-18 as Alex Oriakhi collected a double-double with 18 points and 12 rebounds. Jabari Brown led all scorers with 21 points and Missouri had four players score in double figures.
For Vanderbilt, Rod Odom tied a career-high with 17 points. Kedren Johnson added 11.